New medicine found for treating alpacas with ulcers:
In looking at what brought visitors to my site I noticed that lately a lot of them are inquiring about ulcers in alpacas. It was less than 3 years ago that we lost our beloved Hip Hop Babe to perforated ulcers. You can read all about it by Clicking Here.
It was very sad and as most of you know at the time there was little if anything that could be done. Yes, some people were able to use gastroguard, but if the ulcers were in the third compartment (alpacas have 3 stomachs) then you were out of luck as there was no treatment that could reach it until now.
The Alpaca Research Foundation (ARF) has published the following:
THE ALPACA RESEARCH FOUNDATION,being committed to funding research that will aid in better care and understanding of camelids worldwide, has funded several studies of frequently used ulcer medications for their effectiveness in camelids.
ALPACAS AND ULCERS
Ever have an animal that seemed especially stressed either ‘emotionally’, physically, or both? Did the thought of ulcers then enter your mind as a possible result of that stress?
The veterinary arm of the alpaca industry has utilized several drugs for both ulcer prevention and treatment that were formulated for humans, but until recently had no research data upon which to base the efficacy of those drugs in camelids. We now have some enlightening data to share!
The Bad News First
We know that ulcers can affect both alpacas and llamas of any age, including young crias. Ulcers also have the ability to kill camelids of all ages if they are not adequately treated and resolved. Camelid ulcers occur in the third stomach compartment and have proven somewhat difficult to treat. In addition, the drugs that have been available for use are limited.
Geoffrey Smith, DVM and his colleagues at North Carolina State University, recently published their findings on the use of Gastrogard (oral omeprazole) in llamas. In that study, blood levels were measured over the course of a six day oral treatment at somewhat high doses. Unfortunately, they found that Gastrogard did not produce “concentrations likely to be associated with clinical efficacy in camelids”.
Another Gastrogard study was conducted by Jennifer Lynn Johnson, DVM and colleagues at the University of Minnesota. Their study surgically inserted a cannula into the third stomach compartment of normal alpacas to measure the actual stomach pH. Out of 22 samples taken, none showed a rise in pH to indicate the drug was having any effect.
The Good News NOW
A third study has been conducted by Geoffrey Smith, DVM at North Carolina State University which offers more hope and a much more positive outcome! Pantoprazole has been demonstrated to reduce the acidity of the third compartment when administered either subq or intravenously. The animals used in this study also had a cannula inserted into their third stomach compartment in order to test the pH of the actual stomach contents. When administered either IV or subq, pantoprazole provided a slow, sustained, significant increase in pH, indicating a therapeutic level had been reached! An effective and safe treatment now appears in pantoprazol for the use in both treatment and prophylaxis of camelid ulcers! Thank you Dr. Smith!
Your donated dollars to ARF allow this research project, and many more to continue. Please make your contribution today.
For further information or to contact a member of the ARF board please be sure to visit the Alpaca Research Foundation Website at www.alpacaresearchfoundation.org
Please CLICK HERE to DONATE to support camelid research!
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This is wonderful news, so for all you alpaca breeders be sure to let your vets know!